微量白蛋白尿

微量白蛋白尿
类型	白蛋白尿
分类和外部资源
醫學專科	腎臟科
ICD-11	GB42.0
ICD-9-CM	791.0
MedlinePlus	003591
	[编辑此条目的维基数据]

微量白蛋白尿（英語：Microalbuminuria）是用來描述白蛋白尿水平適度增加的醫學術語。它發生在腎洩漏少量白蛋白進入尿液裡、換言之，即在腎臟腎小球的白蛋白有異常高的滲透性（Vascular permeability）。這個醫學術語"微量白蛋白尿"現在KDIGO（Kidney Disease Improving Global Outcomes/腎臟病改善全球成果）計劃不建議使用，並以"中度增加白蛋白尿"取代之。

病因编辑

血管內皮功能障礙(endothelial dysfunction)的標誌。
腎臟疾病預後的重要標誌：

診斷编辑

微量白蛋白尿定義
	個人	底限	高限	單位
24小時尿液收集		30^[1]	300^[1]	mg/24h (每24小時的毫克白蛋白)
短時間尿液收集		20^[1]	200^[1]	µg/min (每分鐘的微克白蛋白)
定點白蛋白尿樣本		30^[2]	300^[2]	mg/L (每公升尿液的毫克白蛋白)
定點白蛋白尿/肌酸酐比值	女人	3.5^[3]	25^[3] or 35^[3]	mg/mmol (每摩爾肌酸酐的毫克白蛋白)
	女人	30^[3]	400^[3]	μg/mg (每毫克肌酸酐的毫克白蛋白)
	男人	2.5^[3] or 3.5^[3]	25^[3] or 35^[3]	mg/mmol
	男人	30^[3]	300^[3]	μg/mg

參見编辑

白蛋白尿

註釋编辑

^ ^1.0 ^1.1 ^1.2 ^1.3 Page 90 in: Basic Skills in Interpreting Laboratory Data. ISBN 978-1-58528-180-0.
^ ^2.0 ^2.1 Person—microalbumin level (measured) （页面存档备份，存于互联网档案馆） at Australian Institute of Health and Welfare. 01/03/2005
^ ^3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 [1] （页面存档备份，存于互联网档案馆） Thomas I. Justesen, Jens L. A. Petersen, Pia Ekbom, Peter Damm, Elisabeth R. Mathiesen. Albumin-to-creatinine ratio in random urine samples might replace 24-h urine collections in screening for micro- and macroalbuminuria in pregnant woman with type 1 diabetes. Diabetes Care. 2006-4, 29 (4): 924–925 [2019-02-13]. ISSN 0149-5992. PMID 16567839. （原始内容存档于2019-08-22）. 请检查|date=中的日期值 (帮助)

參考文獻编辑

Abid O, Sun Q, Sugimoto K, Mercan D, Vincent JL（英语：Jean-Louis Vincent）. Predictive value of microalbuminuria in medical ICU patients: results of a pilot study. Chest. 2001, 120 (6): 1984–8. PMID 11742932. doi:10.1378/chest.120.6.1984.
Andersen S, Blouch K, Bialek J, Deckert M, Parving HH, Myers BD. Glomerular permselectivity in early stages of overt diabetic nephropathy. Kidney Int. 2000, 58 (5): 2129–37. PMID 11044234. doi:10.1111/j.1523-1755.2000.00386.x.
Heart Outcomes Prevention Evaluation Study Investigators. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Lancet. 2000, 355 (9200): 253–9. PMID 10675071. doi:10.1016/S0140-6736(99)12323-7.
Lemley KV; Abdullah I; Myers BD; et al. Evolution of incipient nephropathy in type 2 diabetes mellitus. Kidney Int. 2000, 58 (3): 1228–37. PMID 10972685. doi:10.1046/j.1523-1755.2000.00223.x.
Lièvre M; Marre M; Chatellier G; et al. The non-insulin-dependent diabetes, hypertension, microalbuminuria or proteinuria, cardiovascular events, and ramipril (DIABHYCAR) study: design, organization, and patient recruitment. DIABHYCAR Study Group. Controlled Clinical Trials（英语：Controlled Clinical Trials）. 2000, 21 (4): 383–96. PMID 10913814. doi:10.1016/S0197-2456(00)00060-X.
Parving HH, Lehnert H, Bröchner-Mortensen J, Gomis R, Andersen S, Arner P. The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. N. Engl. J. Med. 2001, 345 (12): 870–8. PMID 11565519. doi:10.1056/NEJMoa011489.
Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney inter., Suppl. 2013; 3: 1-150.

外部連結编辑

Microalbumin and Urine Albumin/Creatinine Ratio （页面存档备份，存于互联网档案馆） – Lab Tests Online
Online Microalbumin Urine Calculator （页面存档备份，存于互联网档案馆）

[Lee2009-1] 1.0 ^1.1 ^1.2 ^1.3 Page 90 in: Basic Skills in Interpreting Laboratory Data. ISBN 978-1-58528-180-0.

[aihw-2] 2.0 ^2.1 Person—microalbumin level (measured) （页面存档备份，存于互联网档案馆） at Australian Institute of Health and Welfare. 01/03/2005

[Justesen2006-3] 3.00 ^3.01 ^3.02 ^3.03 ^3.04 ^3.05 ^3.06 ^3.07 ^3.08 ^3.09 ^3.10 [1] （页面存档备份，存于互联网档案馆） Thomas I. Justesen, Jens L. A. Petersen, Pia Ekbom, Peter Damm, Elisabeth R. Mathiesen. Albumin-to-creatinine ratio in random urine samples might replace 24-h urine collections in screening for micro- and macroalbuminuria in pregnant woman with type 1 diabetes. Diabetes Care. 2006-4, 29 (4): 924–925 [2019-02-13]. ISSN 0149-5992. PMID 16567839. （原始内容存档于2019-08-22）. 请检查|date=中的日期值 (帮助)

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